Search Results - therapeutics

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Compounds and Methods for Modulating Activity of Calcium Release Channels

Using a new assay for drug development (see Abrj-01), PSU researchers have developed new compounds that may prove useful in the treatment of heart arrhythmia. Ventricular arrhythmias appear to be caused by a calcium leak from the sarcoplasmic reticulum in cardiac muscle, and arrhythmias often lead to heart failure. Drugs that prevent and treat arrhythmias...

Published: 7/23/2009 | Updated: 7/23/2009 | Inventor(s): Jonathan Abramson, Robert Strongin

Keywords(s): Chemistry, Therapeutics

Category(s): Therapeutics

Method and Apparatus for Therapy Dose Response Assessment During Normal Daily Activities with Continuous Monitoring

Methods and necessary apparatus for continuous monitoring of movement disorders. Unlike current medical practices that are conducted briefly using rating scales or less formal examinations, this method allows for continuous monitoring and dose response assessment during the course of normal daily activities.

Published: 7/20/2009 | Updated: 7/20/2009 | Inventor(s): James Mcnames, Mateo Aboy

Keywords(s): Diagnostics, Medical Devices, Therapeutics

Category(s): Medical Devices

Fluorophore-Tagged Cisplatin

Many types of cancer, including carcinomas, lymphomas, sarcomas, and others, are treated with the chemotherapy agent Cisplatin. Based on the element platinum, cisplatin causes apoptosis in cancer cells by cross-linking their DNA. Like many chemotherapy agents, Cisplatin's effectiveness could be improved by better understanding how the body moves it...

Published: 7/24/2009 | Updated: 7/20/2009 | Inventor(s): Robert Strongin, Martha SibriaN-Vazquez, Jorge Escobedo, Peter Streyger

Keywords(s): Biology, Chemistry, Drug Screening, Therapeutics

Category(s): Therapeutics

Quinoline Derivatives and Uses Thereof

David Peyton has developed hybrid drugs to overcome drug resistances in Malaria, Cancer, and Tuberculosis.

Published: 7/20/2009 | Updated: 7/20/2009 | Inventor(s): David Peyton

Keywords(s): Chemistry, Therapeutics

Category(s): Chemistry